Endocrine Abstracts

Introduction: Acromegaly is a rare chronic, and disfiguring endocrine disorder characterized by growth hormone excess, that carries a significant burden of cardiovascular morbidity and mortality; and still unfortunately one of the most important cause of death in acromegaly. The purpose of this study is to describe the cardiovascular events and risk factors concerning patients with acromegaly who are followed up in the endocrinology department of Oujda’s Mohammed VI unive...

Introduction: Pituitary Stalk Interruption Syndrome (PSIS) is characterized by the presence of a thin or absent pituitary stalk, associated with hypoplastic or aplastic anterior pituitary and ectopic posterior pituitary (EPP) on magnetic resonance imaging (MRI). The objective of this study is to describe the clinical, hormonal and radiological aspects of PSIS.Patients and methods: This is a retrospective longitudinal study of 9 cases of PSIS collected in...

Background: In clinical practice, hirsutism is commonly seen among women of fertile age and defined as the presence of terminal hair with male distribution in women.Objective: The aim of the study was to assess the clinical, biochemical and etiologic features of hirsutism in women from the oriental region of Morocco.Materials and methods: 36 female patients presenting with hirsutism at Department of Endocrinology, Mohammed VI Hospi...

Introduction: Primary amenorrhea is an uncommon presentation in reproductive medicine requiring rigorous investigation. Primary amenorrhea is defined by the absence of menstrual cycle in girls after the age of 15 years, with or without the development of secondary sexual characteristics. The objective of the study is to determine the clinical, biological, etiological and therapeutic profile of primary amenorrhea in the Endocrinology-Diabetology department of Mohammed VI Univer...

Introduction: Turner syndrome is a chromosomal abnormality that affects phenotypic females who have one intact X chromosome and complete or partial absence of the second sex chromosome. In this genetic disease, the karyotype ranges from complet 45, X to forms of mosaicism in which a normal cell line (46, XX or 46, XY) or a second (or third) abnormal cell line is found. Mosaic turner syndrome (MTS) has a heterogeneous clinical presentation as well as a varied presence of malfor...

Introduction: Cushing’s disease is caused by endogenous hypercotisolism, due to the hypersecretion of the adenocorticotropic hormone (ACTH) by an ACTH-secreting pituitary adenoma. However, some patients with Cushing’s disease have no visible adenoma on MRI. The goal of this study is to review the clinical features, diagnosis and medical preparation of patients with Cushing’s disease.Material and Methods: A retrospective study including ...

Introduction: Acromegaly is a rare disease characterized by somatotropic hypersecretion. The disease is associated with multiple significant comorbidities and increased mortality. The purpose of this study is to describe the epidemiological, clinical, para-clinical and therapeutic features of Acromegaly disease.Patients and Methods: This is a retrospective study including 12 patients with acromegaly in the Endocrinology Diabetology Department of Oujda&#8...

Introduction: Cushing’s syndrome is a rare condition, resulting from chronic exposure to excessive circulating levels of glucocorticoids. This condition is highly associated with complications such as cardiovascular and metabolic disorders. This study aims to review the clinical characteristics, diagnosis and treatment of patients with ACTH-dependent Cushing’s syndrome.Material and Methods: A descriptive and comparative study carried out in t...

Introduction: Turner syndrome is one of the most common chromosomal abnormalities, with a reported prevalence of one in every 2.500 live-born girls. The phenotype includes short stature, primary ovarian failure, and other characteristics resulting from the consequences of fetal lymphedema and skeletal abnormalities. Turner syndrome can be associated with multiple defects: cardiovascular, renal, auditory, and skeletal. The aim of our study was to detect the prevalence of cardia...

Introduction: Hirsutism is a condition featuring an excessive growth of terminal hair at the woman’s androgen-dependent areas, which develops in a distribution model similar to that of men. It is one of the most common disorders in women during reproductive age. It affects up to 1 in 7 women. The objective of this work was to study the clinical and etiological aspects of hirsutism.Material and Methods: This is a retrospective descriptive study invo...